| 陈慕芝,谢志敏,李霄鹏,等.原发性干燥综合征中西医病证结合诊疗体系构建探讨[J].浙江中医药大学学报,2024,48(8):942-947. |
| 原发性干燥综合征中西医病证结合诊疗体系构建探讨 |
| Discussion on the Construction of Combined Diagnosis and Treatment System of Chinese and Western Medicine for Primary Sj?gren’s Syndrome |
| DOI：10.16466/j.issn1005-5509.2024.08.006 |
| 中文关键词: 原发性干燥综合征 燥痹 中西医结合 病证结合 辨证论治 辨病论治 辨证分型 诊疗体系 |
| 英文关键词: primary Sj?gren’s syndrome dry paralysis combination of Chinese and western medicine combination of disease and syndrome treatment according to syndrome differentiation treatment according to disease differentiation syndrome differ classification diagnosis and treatment system |
| 基金项目:国家中医药管理局科技司-浙江省中医药管理局共建科技计划项目(GZY-ZJ-KJ-23016) |
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| 中文摘要: |
| [目的] 构建原发性干燥综合征(primary Sj?gren’s syndrome，pSS)中西医病证结合诊疗体系，为临床实践提供实用和规范的诊疗方案指导。[方法] 通过查阅文献，归纳总结pSS的病因病机、治则治法，结合中西医诊治pSS现状及本团队多年临床经验，参照pSS西医标准进行诊断和病情评估，并根据不同的临床表现或系统受累进行分型，再根据中医四诊合参进行辨证论治，构建pSS中西医病证结合诊疗体系。[结果] pSS中西医病证结合诊疗体系囊括了pSS临床常见证型，具体分为气阴两虚证、燥热蕴毒证、燥毒瘀结证、燥热伤肺证、肾气不固证、肝阴亏虚证、气(阴)虚络瘀证、气血亏虚证、阴虚热毒证等9种证型，每种证型均制定了详尽的理法方药。[结论] pSS中西医病证结合诊疗体系为临床诊治pSS提供了良好的范式，具有一定的临床价值和现实意义。 |
| 英文摘要: |
| [Objective] To explore the combined diagnosis and treatment system of Chinese and western medicine for primary Sj?gren’s syndrome(pSS)， and to provide practical and standardized diagnostic and therapeutic directions for professional practice. [Methods] By reviewing the literature， summarizing the etiology and pathogenesis of pSS， the rules and treatments of pSS， combining the current situation of pSS diagnosis and treatment in Chinese and western medicine and our team’s many years of clinical experience， this paper refers to the western medical standards for the diagnosis and evaluation of pSS and carries out typing according to different clinical manifestations or systemic involvement， and then carries out diagnosis and treatment according to the four diagnostic elements of Chinese medicine， so as to build up the combined diagnostic and treatment system of pSS of Chinese and western medicine， combining disease with type. [Results] The combined diagnosis and treatment system of Chinese and western medicine for pSS included 9 common clinical patterns of pSS， including Qi and Yin deficiency， dry heat and toxin， dry toxin stasis， dry heat injuring the lungs， kidney Qi failure， liver and Yin deficiency， Qi(Yin) deficiency and collateral stasis， Qi and blood deficiency， and Yin deficiency and heat and toxin， etc.， and each of which had been formulated into a detailed rationale， methodology， prescription and medicine. [Conclusion] The combined diagnosis and treatment system of Chinese and western medicine for pSS provides a good paradigm for clinical diagnosis and treatment of pSS， which will generate certain clinical value and practical implications. |
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